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16 nursing jobs in Sioux Falls, SD

Sioux Falls blends Midwestern friendliness with urban energy. South Dakota's largest city offers a growing healthcare sector, clean parks along the Big Sioux River, and a vibrant downtown. Nurses enjoy no state income tax, short commutes, and genuine community in this steadily expanding metro.

Listed salaries range $60k–$208k/yr across 7 postings that disclose pay.

Good Samaritan workplace
Good Samaritan — a workplace named in a current Sioux Falls posting

Good Samaritan

RN - Full Time Days Weekends - SF Center

Sioux Falls, South Dakota

$34–$48/hrView role
Sanford Health workplace
Workplace photo

Sanford Health

RN - Registered Nurse - Med Surg Float Pool - Days

Sioux Falls, South Dakota 57117

12 Hour shift

$32–$48/hrView role
Avera workplace
Employer photoHealth system employer
Avera logo

Avera

RN - Outpatient Services | Avera Heart Hospital

Sioux Falls, South Dakota

Pay not listedView role
Avera Health workplace
Employer photoHealth system employer
Avera Health logo

Avera Health

Registered Nurse (RN) | Virtual OB | On Site Avera McKennan

Sioux Falls, South Dakota

Pay not listedView role
PorchLight Services photo
Employer photoHiring organization

PorchLight Services

RN / LPN

Sioux Falls, South Dakota 57105

8 Hour shift

$29–$40/hrView role
My Marijuana Cards photo
Employer photo
My Marijuana Cards logo

My Marijuana Cards

Sioux Falls APRN Medical Cannabis Industry

Sioux Falls, SD

$50/hrView role
U.S. Department of Veterans Affairs workplace
Employer photoHiring organization

U.S. Department of Veterans Affairs

Registered Nurse - Home Telehealth

Sioux Falls, SD

Day shift

Pay not listedView role
LifeScape photo
Employer photo
LifeScape logo

LifeScape

Registered Nurse - Children's Services - Residential

Sioux Falls, South Dakota 57106

Pay not listedView role

Correctional Medical Management, LLC

Registered Nurse - Nights

Sioux Falls, South Dakota

$41–$45/hrView role

Veterans Health Administration

Registered Nurse- Inpatient Mental Health

Sioux Falls, South Dakota

Travel contract

Pay not listedView role
TNAA Healthcare logo

TNAA Healthcare

Staffing partner

RN Clinic

Sioux Falls, SD

Travel contract

$2,300/wkView role

Good Samaritan

RN - Full Time Nights - SF Village

Sioux Falls, South Dakota 57106

Night shift

$34–$48/hrView role

Sanford Health

RN Infusion - Outpatient Care Center

Sioux Falls, South Dakota 57105

$32–$48/hrView role
Avera Health logo

Avera Health

Registered Nurse (RN) | Comprehensive Pain Clinic

Sioux Falls, South Dakota

Day shift

Pay not listedView role
LifeScape logo

LifeScape

Registered Nurse - Children's Services - Residential

Sioux Falls, SD 57106

Pay not listedView role

Veterans Health Administration

Registered Nurse - Home Health

Sioux Falls, South Dakota

Pay not listedView role

Good Samaritan

Rehab RN - Full Time Weekend Nights - SF Village

Sioux Falls, South Dakota 57106

Night shift

$34–$48/hrView role

Sanford Health

RN - Registered Nurse - Short Stay FT Days

Sioux Falls, South Dakota 57105

$32.00 - $48.00View role

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